Hand Chemistry is a hand lotion from Deciem’s The Chemistry Brand that claims to target 8 signs of hand aging (brightness, elasticity, firmness, smoothness, density, evenness, hydration and texture), with noticeable results in 11 days.

Ingredients: Aqua (Water), Caprylic/Capric Triglyceride, Propanediol, Cetearyl Glucoside, Cetearyl Alcohol, Glycerin, Cetyl Alcohol, Plukenetia Volubilis Seed Oil, Copper Lysinate/Prolinate, Plantago Lanceolata Leaf Extract, Methylglucoside Phosphate, Proline, Alanine, Serine, Pseudoalteromonas Ferment Extract, Tremella Fuciformis Sporocarp Extract, Tocopherol, Betaine, Cellulose, Xanthan Gum, Sodium Polyacrylate, Sodium Phosphate, Sodium Hydroxide, Potassium Sorbate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin, Parfum (Fragrance), Limonene, Linalool
Some unfamiliar ingredients – Plukenetia Volubilis seed oil, also known as sacha inchi oil, is from the Amazon rainforest rich in omega 3 fatty acids. Copper lysinate/prolinate is an amino acid/mineral complex that has the potential to target signs of aging. Plantago Lanceolata (also known as plantain) leaf extract has soothing and anti-inflammatory properties. Hand Chemistry contains fragrance and limonene and linalool are used as fragrance as well.
Directions: Apply to clean hands morning and evening.
I am 39 years old and have noticed fine lines and dull, thin and dry skin on my hands over the last couple years. I’ve used Hand Chemistry for 2 months so far, morning and evening, a bit less than one pump.
This is quite a thick cream. The fragrance itself is not bad or particularly overpowering and fades after a bit, but there is something about it that really bothered me for the first few uses, so much so that I got headaches (which is unusual; I am not generally sensitive to smells). After a few uses I guess I got used to it and no longer get headaches. The scent is an odd, sweet, cherry, bubble gum smell.
The lotion absorbs quite quickly with no greasy or heavy residue that leaves a protective moisture barrier after massaging into the hands. If I use too much product, or continue to massage in after the lotion is mostly absorbed, the product pills on the skin. The hands feel immediately hydrated, smooth and soft, however, this feeling does not too long, nor lasts past a hand wash (or even just a rinse with water) as with some other hand lotions I’ve tried.

Hand Chemistry provided some surface hydration; I expected a better level of moisture after 2 months of twice-a-day use. My hands still feel dry.

I didn’t feel or notice any improvement in brightness or smoothing of fine lines just looking at my hands, but in the photos above, there is noticeable improvement in these areas, particularly with brightness around the knuckles and an overall smoothed appearance of fine lines on the hands. My skin does not feel like it has improved density.
I am undecided about this product; I had hoped hydration and moisture to be better, but there is improved brightness and smoothing of fine lines. I recently got a hand/body lotion with 10% glycolic acid, so maybe using this or another more hydrating lotion (my favorite is from Akita Rosewater) under the Hand Chemistry would show more improvement. I also wonder if I can get similar benefit with using a routine similar to facial skin care with hyaluronic acid, a toner, niacinamide and a hydrating lotion perhaps; so a few things to try in the coming months.
Thank you for reading.